Du kan använda union all
för att avpivotera din datauppsättning och sedan aggregering:
select disease, count(*) total
from (
select disease from mytable
union all select additional_disease1 from mytable
union all select additional_disease2 from mytable
union all select additional_disease3 from mytable
union all select additional_disease4 from mytable
) t
group by disease
order by total desc, disease